Memory loss in Alzheimer's disease: are the alterations in the UPR network involved in the cognitive impairment?
نویسندگان
چکیده
1 Faculty of Medicine, Biomedical Neuroscience Institute, University of Chile, Santiago, Chile 2 Program of Cellular and Molecular Biology, Center for Molecular Studies of the Cell, Institute of Biomedical Sciences, University of Chile, Santiago, Chile 3 Neurounion Biomedical Foundation, Santiago, Chile 4 Department of Immunology and Infectious diseases, Harvard School of Public Health, Boston, MA, USA *Correspondence: [email protected] or [email protected]
منابع مشابه
The recent development in synthesis and pharmacological evaluation of small molecule to treat Alzheimer's diseases: A review
Alzheimer's disease is a neurological disorder in which the death of brain cells causes memory loss and cognitive decline. A neurodegenerative type of dementia, the disease starts mild and gets progressively worse. Like all types of dementia, Alzheimer's is caused by brain cell death. The most common presentation marking Alzheimer's dementia is where symptoms of memory loss are the most promine...
متن کاملThe recent development in synthesis and pharmacological evaluation of small molecule to treat Alzheimer's diseases: A review
Alzheimer's disease is a neurological disorder in which the death of brain cells causes memory loss and cognitive decline. A neurodegenerative type of dementia, the disease starts mild and gets progressively worse. Like all types of dementia, Alzheimer's is caused by brain cell death. The most common presentation marking Alzheimer's dementia is where symptoms of memory loss are the most promine...
متن کاملP135: The Role of Amyloid Beta-Peptides and Tau Protein in Alzheimer\'s Disease
Alzheimer's desease is the most common age-related neurodegenerative disorder, and cognitive problems such as defects in learning and memory are of its symptoms. Among the factors involved in the pathogenesis of the disease are biochemical disorders in protein production, oxidative stress, decreased acetylcholine secretion and inflammation of the brain tissue. Extra-neuronal accumulation ...
متن کاملThe effect of high-intensity interval training on cognitive and memory impairments in obesity and diabetes: A review study
The effect of high-intensity interval training on cognitive and memory impairments in obesity and diabetes: A review study Background and Aim nowadays, industrialization has reduced physical activity and lifestyle changes, resulting in the spread of lifestyle-related diseases. A common feature in most diseases associated with the new lifestyle is obesity. Obesity as a multifactorial disease i...
متن کاملبررسی تاثیر پروژسترون بر پراکسیداسیون لیپیدی و اختلال حافظه ناشی از مدل آلزایمر حاصل از تزریق موضعی استرپتوزوتوسین در رت
Introduction: Alzheimer’s disease is one of the most prevalent brain neurodegenerative diseases and the most common cognitive deficits are memory dysfunction and spatial perception impairment. Progesterone has a neorostroid action in hippocampal neurogenesis, synaptic stability and spatial learning and memory and has antioxidant effect. Since oxidative stress is involved in the pathogenes...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره 6 شماره
صفحات -
تاریخ انتشار 2014